Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27630230 | 0.98 | NAAA (0.65) | NAAANPC1TDP1ALDH1A1LMNA | |
| SCHEMBL805464 | 0.83 | L3MBTL1 (0.72) | NPC1TDP1ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28021541 | 0.81 | L3MBTL1 (0.69) | NPC1TDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL84806 | 0.81 | L3MBTL1 (0.73) | NPC1TDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3839653 | 0.81 | L3MBTL1 (0.73) | NPC1TDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16333764 | 0.80 | NAAA (1.00) | NAAANPC1TDP1ALDH1A1LMNA | |
| SCHEMBL9762642 | 0.79 | — | — | |
| SCHEMBL12282092 | 0.78 | MAPT (0.76) | NPC1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL12282111 | 0.76 | MEN1 (0.76) | NPC1TDP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4198757 | 0.76 | NAMPT (0.65) | ALDH1A1LMNARAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1469862-A | 2, 2-diphenylbutanamide derivatives and drugs containing the same | SS制药株式会社 | 2004-01-21 | — | — | CN | disclosed |
| CN-1304929-A | 4-hydroxy-4-phenyl piperidine derivative and medicine containing said derivative | SS PHARMACEUTICAL CO (JP) | 2001-07-25 | — | — | CN | disclosed |