Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27530949 | 0.98 | NAAA (0.67) | NAAANPC1TDP1ALDH1A1RAB9A | |
| SCHEMBL3839653 | 0.84 | L3MBTL1 (0.73) | NPC1TDP1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL84806 | 0.84 | L3MBTL1 (0.73) | NPC1TDP1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL805464 | 0.82 | L3MBTL1 (0.72) | NPC1TDP1ALDH1A1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL28021541 | 0.80 | L3MBTL1 (0.69) | NPC1TDP1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16333764 | 0.79 | NAAA (1.00) | NAAANPC1TDP1ALDH1A1RAB9A | |
| SCHEMBL9762642 | 0.78 | — | — | |
| SCHEMBL12282092 | 0.77 | MAPT (0.76) | NPC1ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17087869 | 0.76 | NPC1 (0.96) | NAAANPC1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL6285963 | 0.76 | NPC1 (0.96) | NAAANPC1TDP1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816524-A | Selective serotonin 2A/2C receptor inverse agonists for the treatment of neurodegenerative diseases | ACADIA PHARM INC (US) | 2006-08-09 | — | — | CN | claimed |
| CN-1816524-B | Selective serotonin 2A/2C receptor inverse agonists for the treatment of neurodegenerative diseases | ACADIA PHARM INC | 2012-06-27 | — | — | CN | disclosed |
| CN-1816524-A | Selective serotonin 2A/2C receptor inverse agonists for the treatment of neurodegenerative diseases | ACADIA PHARM INC (US) | 2006-08-09 | — | — | CN | disclosed |
| CN-1777612-A | New piperidinylamino-thieno[2,3-d] pyrimidine compounds | PREDIX PHARMACEUTICALS HOLDING (US) | 2006-05-24 | — | — | CN | disclosed |