Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.46 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832605 | 0.79 | CA2 (0.46) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1019800 | 0.77 | TSHR (0.50) | CA2CA1CA9CA12CA14 | |
| SCHEMBL5351434 | 0.76 | TSHR (0.48) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1653521 | 0.75 | CA2 (0.42) | CA2CA1CA9CA12CA14 | |
| SCHEMBL28742455 | 0.75 | CA1 (0.42) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1705972 | 0.75 | CA2 (0.42) | CA2CA1CA9CA12CA14 | |
| Benzoic Acid SCHEMBL28002531 | 0.74 | TSHR (0.74) | CA2CA1CA9CA12CA14 | |
| SCHEMBL11538453 | 0.72 | PTGS2 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL11538451 | 0.72 | PTGS2 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL11544195 | 0.70 | PTGS2 (0.46) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1237164-A | compounds useful as farnesyl-protein transferase inhibitors | SCHERING CORP (US) | 1999-12-01 | — | — | CN | disclosed |