Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL29263993 | 0.86 | AKT1 (0.48) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| SCHEMBL7764796 | 0.83 | STS (0.46) | TDP1PARP1L3MBTL1CA2CA1 | |
| SCHEMBL27552924 | 0.79 | CES1 (0.52) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| SCHEMBL11832605 | 0.77 | CA2 (0.46) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| Benzoic Acid SCHEMBL28002531 | 0.77 | TSHR (0.74) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| SCHEMBL1728427 | 0.77 | CES1 (0.50) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| SCHEMBL6844400 | 0.77 | CES1 (0.50) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| SCHEMBL27531908 | 0.77 | CA2 (0.46) | TSHRCYP3A4MAPTTDP1CYP2C19 | |
| SCHEMBL2113832 | 0.76 | ALDH1A1 (0.52) | TDP1CES1CES2ALDH1A1CA2 | |
| SCHEMBL9068783 | 0.76 | CES2 (0.52) | TSHRMAPTL3MBTL1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421343-A | Manufacturing process of buried copper plate | 江西技研新阳电子有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-116832791-B | Magnetic covalent organic framework material, preparation method and application thereof | 石家庄市疾病预防控制中心（石家庄市卫生检测中心） | 2024-09-10 | — | — | CN | claimed |
| CN-117092227-A | Method for rapidly screening multiple veterinary drug residues in milk | 黑龙江飞鹤乳业有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116773689-A | Method for rapidly screening various antibacterial drug residues in livestock manure and application thereof | 中国动物卫生与流行病学中心 | 2023-09-19 | — | — | CN | claimed |
| CN-116678984-A | Method for detecting pesticide and antibiotic residues in paddy | 中山市农产品质量安全检验所(中山市水生动物疫病预防控制中心) | 2023-09-01 | — | — | CN | claimed |
| CN-115232037-A | Preparation method of benzoyl sulfonamide-N-substituted benzamide compound | 郑州手性药物研究院有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-114669280-A | Purification filler for sulfonamide residues and pretreatment method | 深圳市易瑞生物技术股份有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-114487176-A | Rapid screening method for dangerous substances in aquatic products | 大连海洋大学 | 2022-05-13 | — | — | CN | claimed |
| CN-108051507-B | Method for analyzing residual veterinary drugs in mutton | 新疆畜牧科学院畜牧业质量标准研究所（新疆维吾尔自治区种羊与羊毛羊绒质量安全监督检验中心） | 2020-10-09 | — | — | CN | claimed |
| CN-110204491-A | A kind of synthetic method of chirality 3,4- dihydro-isoquinoline ketone compound | 台州学院 | 2019-09-06 | — | — | CN | claimed |
| CN-1186332-C | Novel thyroid receptor ligands and method II | KAROBIO AB (SE) | 2005-01-26 | — | — | CN | claimed |
| US-6815439-B2 | PYRROLO(2,3-B)PYRIDINE DERIVATIVES AS CYCLIN-DEPENDENT KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2004-11-09 | — | — | US | claimed |
| US-20040072836-A1 | Substituted aza-oxindole derivatives | HARRIS PHILIP ANTHONY (US) | 2004-04-15 | — | — | US | claimed |
| US-6624171-B1 | Useful as cyclin dependent kinase 11 inhibitors, for preventing/reducing the severity of epithelial cytotoxicity side-effects (e.g., alopecia, plantar- palmar syndrome, mucositis) induced by chemotherapy and/or radiation therapy | SMITHKLINE BEECHAM CORPORATION | 2003-09-23 | — | — | US | claimed |
| EP-1180105-B1 | SUBSTITUTED AZA-OXINDOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-05-14 | — | — | EP | claimed |
| JP-2003502280-A | — | — | 2003-01-21 | — | — | JP | claimed |
| CN-1337953-A | Novel thyroid receptor ligands and method II | KAROBIO AB (SE) | 2002-02-27 | — | — | CN | claimed |
| EP-1180105-A2 | SUBSTITUTED AZA-OXINDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2002-02-20 | — | — | EP | claimed |
| WO-2000055159-A2 | SUBSTITUTED AZA-OXINDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-09-21 | — | — | WO | claimed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072836-A1 | Substituted aza-oxindole derivatives | CCNI, AZI2, CDKN1A | TSHR 2075/4885CYP3A4 3341/4885MAPT 4201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.