Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624784 | 0.85 | TSHR (0.53) | TSHRKDM4EFOLH1PLA2G2APTPN1 | |
| SCHEMBL4521739 | 0.84 | TSHR (0.72) | TSHRKDM4EFOLH1PLA2G2APTPN1 | |
| SCHEMBL27595060 | 0.84 | TSHR (0.54) | TSHRKDM4EFOLH1PTPN1CA1 | |
| SCHEMBL27542160 | 0.82 | TSHR (0.53) | TSHRKDM4EFOLH1PTPN1PTPN2 | |
| SCHEMBL27869431 | 0.82 | TSHR (0.53) | TSHRKDM4E | |
| Terephthalic Acid SCHEMBL9858389 | 0.81 | LOXL2 (0.56) | TSHRFOLH1LOXL2ENPP2 | |
| Cyclopropane SCHEMBL27582578 | 0.79 | RXRA (0.49) | TSHR | |
| Isophthalic Acid SCHEMBL9858510 | 0.79 | FOLH1 (0.58) | FOLH1LOXL2CA1CA2CA9 | |
| SCHEMBL2818924 | 0.79 | KDM4E (0.47) | TSHRKDM4ELOXL2PTPN1CA1 | |
| SCHEMBL27994405 | 0.79 | TSHR (0.55) | TSHRKDM4EFOLH1PTPN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132939-A | Process for producing tetrazolinone compound | 住友化学株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-1252069-C | 2-aryl-naphthyridin-4-ones as antitumor agents | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2006-04-19 | — | — | CN | disclosed |