SCHEMBL2818924

SCHEMBL2818924

NCc1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
TSHR P16473 3/20 0.44
TP53 P04637 1/20 0.42
MAPT P10636 3/20 0.42
POLB P06746 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
GAA P10253 2/20 0.42
CA4 P22748 2/20 0.42
CA9 Q16790 2/20 0.42
CA6 P23280 1/20 0.42
PTGS2 P35354 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
PTPN1 P18031 1/20 0.42
HTR7 P34969 1/20 0.41
ALDH1A1 P00352 4/20 0.40
CDC25B P30305 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17059386 0.87 AKR1C3 (0.41) KDM4ETSHRTP53MAPTPOLB
SCHEMBL11854246 0.86 KDM4E (0.48) KDM4ETSHRTP53MAPTPOLB
SCHEMBL27994405 0.85 TSHR (0.55) KDM4ETSHRMAPTPOLBCA1
SCHEMBL21937348 0.84 ACE2 (0.43) KDM4EMAPTGAAHTR7ALDH1A1
SCHEMBL27283211 0.83 TSHR (0.46) KDM4ETSHRTP53MAPTPOLB
SCHEMBL8482484 0.82 KDM4E (0.48) KDM4ETSHRTP53MAPTPOLB
Hydrochloric Acid SCHEMBL27760143 0.82 TSHR (0.44) KDM4ETSHRTP53MAPTPOLB
SCHEMBL9346007 0.82 CA12 (0.59) KDM4ETSHRTP53MAPTPOLB
SCHEMBL8482490 0.82 ACE2 (0.50) KDM4ETSHRTP53MAPTPOLB
SCHEMBL1355542 0.82 ALDH1A1 (0.52) KDM4ETSHRTP53MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110305038-A - 2,3 dimethyl azobenzene of 4- aminomethyl isophthalate and its preparation method and application 郑州大学 2019-10-08 CN claimed
CN-110305038-A - 2,3 dimethyl azobenzene of 4- aminomethyl isophthalate and its preparation method and application 郑州大学 2019-10-08 CN disclosed
CN-110305038-A - 2,3 dimethyl azobenzene of 4- aminomethyl isophthalate and its preparation method and application 郑州大学 2019-10-08 CN disclosed
US-20100304381-A1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS Life Technologies Corporation (US) 2010-12-02 US disclosed
US-7687236-B2 Fluorescent nucleobase conjugates having anionic linkers APPLIED BIOSYSTEMS, LLC (US) 2010-03-30 US disclosed
US-7687236-B2 Fluorescent nucleobase conjugates having anionic linkers APPLIED BIOSYSTEMS, LLC (US) 2010-03-30 US disclosed
CN-101681130-A Material stripping method for wafer reclamation ADVANCED TECH MATERIALS 2010-03-24 CN disclosed
EP-1317464-B1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS APPLERA CORP (US) 2009-05-13 EP disclosed
EP-1317464-B1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS APPLERA CORP (US) 2009-05-13 EP disclosed
US-20090092986-A1 Fluorescent Nucleobase Conjugates Having Anionic Linkers APPLIED BIOSYSTEMS INC. (US) 2009-04-09 US disclosed
CN-100393703-C 1,2,3,4-tetrahydroisoquinoline derivatives ACTELION PHARMACEUTICALS LTD (CH) 2008-06-11 CN disclosed
CN-100356979-C Integrin expression inhibitors EISAI CO LTD (JP) 2007-12-26 CN disclosed
CN-101010059-A Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE (US) 2007-08-01 CN disclosed
US-20050250119-A1 Fluorescent nucleobase conjugates having anionic linkers APPLERA CORPORATION (US) 2005-11-10 US disclosed
US-6811979-B2 NUCLEOTIDE DERIVATIVE FOR USE IN SEQUENCE DETERMINATION OF NUCLEIC ACID MOLECULE APPLERA CORPORATION 2004-11-02 US disclosed
EP-1317464-A2 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS Applera Corporation (US) 2003-06-11 EP disclosed
CN-1416420-A 1,2,3, 4-tetrahydroisoquinoline derivatives ACTELION PHARMACEUTICALS LTD (CH) 2003-05-07 CN disclosed
CN-1396833-A Integrin expression inhibitors EISAI CO LTD (JP) 2003-02-12 CN disclosed
US-20020102590-A1 Fluorescent nucleobase conjugates having anionic linkers PE CORPORATION (NY) (US) 2002-08-01 US disclosed
WO-2002030944-A2 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS APPLERA CORPORATION (US) 2002-04-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250119-A1 Fluorescent nucleobase conjugates having anionic linkers DNTT, DUT, NT5C3B KDM4E 1295/4885TSHR 3422/4885TP53 1659/4885
US-20100304381-A1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS DNTT, DUT, NT5C3B KDM4E 1295/4885TSHR 3422/4885TP53 1659/4885
US-20020102590-A1 Fluorescent nucleobase conjugates having anionic linkers DNTT, DUT, NT5C3B KDM4E 1295/4885TSHR 3422/4885TP53 1659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.