Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.71 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.71 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.71 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL2473794 | 1.00 | — | — | |
| Glycine SCHEMBL19326549 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL20528834 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL27552443 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL629430 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL599168 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL844613 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL29055914 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL782087 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL29055907 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768523-B | There is 0.30 or the more personal care composition of lossy angle tangent value at 10 DEG C | 宝洁公司 | 2017-08-15 | — | — | CN | claimed |
| CN-104768523-A | Personal care compositions having a tan delta of 0.30 or more at 10 DEG C | PROCTER & GAMBLE | 2015-07-08 | — | — | CN | claimed |
| CN-114423405-B | Personal care compositions comprising anti-dandruff agents | 宝洁公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118055752-A | Personal cleansing compositions containing organic acids having pKa greater than 2.7 | 宝洁公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-118043026-A | Non-therapeutic method for helping human skin maintain its natural defenses against bacteria | 宝洁公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117500479-A | Cleaning compositions with pyrrolidone carboxylic acid | 宝洁公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116568263-A | Hair care composition comprising malodor reduction materials | 宝洁公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114423405-A | Personal care compositions comprising an anti-dandruff agent | 宝洁公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108366935-B | Pet care cleansing compositions | 勃林格殷格翰动物保健美国公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113893189-A | Pet care cleansing compositions | 勃林格殷格翰动物保健美国公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-112566615-A | Rinse-off cleansing compositions | 宝洁公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-104202987-B | Personal nursing method | 宝洁公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-104768523-B | There is 0.30 or the more personal care composition of lossy angle tangent value at 10 DEG C | 宝洁公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-104902869-A | Personal care compositions | PROCTER & GAMBLE | 2015-09-09 | — | — | CN | disclosed |
| CN-104862129-A | Cleansing Bar Compositions Comprising A High Level Of Water | PROCTER & GAMBLE | 2015-08-26 | — | — | CN | disclosed |
| CN-104837478-A | Personal care compositions | PROCTER & GAMBLE | 2015-08-12 | — | — | CN | disclosed |
| CN-104768523-A | Personal care compositions having a tan delta of 0.30 or more at 10 DEG C | PROCTER & GAMBLE | 2015-07-08 | — | — | CN | disclosed |
| CN-104519860-A | Personal care compositions having dried zinc pyrithione-polymer aggregates | PROCTER & GAMBLE | 2015-04-15 | — | — | CN | disclosed |
| CN-104363761-A | Personal care compositions with dried zinc pyrithione | PROCTER & GAMBLE | 2015-02-18 | — | — | CN | disclosed |
| CN-1283101-A | Improved antiperspirant activity and formulations made therefrom | COLGATE PALMOLIVE CO (US) | 2001-02-07 | — | — | CN | disclosed |