Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.71 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.71 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.71 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL2473794 | 1.00 | — | — | |
| Glycine SCHEMBL27533136 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL19326549 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL27552443 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL629430 | 1.00 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL599168 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL844613 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL29055914 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL782087 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Glycine SCHEMBL29055907 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250387316-A1 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS FOR INCREASED SKIN LUBRICITY | PROCTER & GAMBLE (US) | 2025-12-25 | — | — | US | disclosed |
| US-12420120-B2 | Antiperspirant and deodorant compositions for increased skin lubricity | THE PROCTER & GAMBLE COMPANY (US) | 2025-09-23 | — | — | US | disclosed |
| CN-117084953-A | Hair care or hair cleaning composition or skin care or skin cleaning composition | 魏德曼控股股份公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4265237-A1 | HAIR CARE OR HAIR CLEANSING OR SKIN CARE OR SKIN CLEANSING COMPOSITION | Weidmann Holding AG (CH) | 2023-10-25 | — | — | EP | disclosed |
| CN-116919865-A | Dry mixture | 魏德曼控股股份公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-3606500-B1 | PERSONAL CARE COMPOSITION | WEIDMANN HOLDING AG (CH) | 2023-10-04 | — | — | EP | disclosed |
| EP-4239124-A2 | DRY MIXTURE | Weidmann Holding AG (CH) | 2023-09-06 | — | — | EP | disclosed |
| CN-110505868-B | Personal care compositions | 魏德曼控股股份公司 | 2023-07-28 | — | — | CN | disclosed |
| US-11696876-B2 | Hair care or hair cleansing composition or skin care or skin cleansing composition | Weidmann Holdino AG (CH) | 2023-07-11 | — | — | US | disclosed |
| US-20230010214-A1 | DEODORIZING COMPOSITION | AQDOT LIMITED (GB) | 2023-01-12 | — | — | US | disclosed |
| EP-3390483-B1 | ENCAPSULATION | PROCTER & GAMBLE (US) | 2022-05-18 | — | — | EP | disclosed |
| US-11278475-B2 | Personal care composition | WEIDMANN HOLDING AG (CH) | 2022-03-22 | — | — | US | disclosed |
| EP-3206782-B1 | CONTROLLED RELEASE DUAL WALLED MICROCAPSULES | PROCTER & GAMBLE (US) | 2021-12-15 | — | — | EP | disclosed |
| US-20210308492-A1 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS FOR INCREASED SKIN LUBRICITY | THE PROCTER & GAMBLE COMPANY | 2021-10-07 | — | — | US | disclosed |
| WO-2021116692-A2 | DEODORIZING COMPOSITION | AQDOT LIMITED (GB) | 2021-06-17 | — | — | WO | disclosed |
| US-20210007941-A1 | PERSONAL CARE COMPOSITION | WEIDMANN HOLDING AG (CH) | 2021-01-14 | — | — | US | disclosed |
| EP-3206781-B1 | HIGH STRENGTH MICROCAPSULES | PROCTER & GAMBLE (US) | 2020-07-15 | — | — | EP | disclosed |
| EP-3606500-A1 | PERSONAL CARE COMPOSITION | Weidmann Holding AG (CH) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018185230-A1 | PERSONAL CARE COMPOSITION | WEIDMANN HOLDING AG (CH) | 2018-10-11 | — | — | WO | disclosed |
| CN-107847418-A | Silk-based moisturizer composition and method thereof | 丝绸医疗公司 | 2018-03-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12420120-B2 | Antiperspirant and deodorant compositions for increased skin lubricity | DSG1, DEK, CUTA | GLRA1 3706/4885SLC6A9 3949/4885OR51E2 136/4885 |
| US-20210308492-A1 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS FOR INCREASED SKIN LUBRICITY | DSG1, DEK, CUTA | GLRA1 3706/4885SLC6A9 3949/4885OR51E2 136/4885 |
| US-20250387316-A1 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS FOR INCREASED SKIN LUBRICITY | DSG1, DSTN, CUTA | GLRA1 4371/4885SLC6A9 3680/4885OR51E2 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.