Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504941 | 1.00 | METAP1 (0.37) | METAP1ALOX5DPP4SLC1A3SLC1A2 | |
| SCHEMBL1449256 | 1.00 | METAP1 (0.37) | METAP1ALOX5DPP4SLC1A3SLC1A2 | |
| SCHEMBL7375737 | 0.98 | ALOX5 (0.34) | METAP1ALOX5DPP4SLC1A3SLC1A2 | |
| SCHEMBL7375837 | 0.93 | — | — | |
| SCHEMBL7608856 | 0.88 | — | — | |
| SCHEMBL8943205 | 0.80 | CPB2 (0.36) | — | |
| SCHEMBL2640244 | 0.80 | CPB2 (0.36) | — | |
| SCHEMBL21211687 | 0.79 | KDM4E (0.38) | METAP1CTSK | |
| SCHEMBL27534752 | 0.79 | KDM4E (0.38) | METAP1CTSK | |
| SCHEMBL7105061 | 0.78 | METAP1 (0.52) | METAP1ALOX5METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564588-B1 | HEXAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | ABBOTT LAB (US) | 1997-02-12 | — | — | EP | claimed |
| US-5387671-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-02-07 | — | — | US | claimed |
| US-5386011-A | Antiinflammatory agents; also, peptidomimetic compounds, i,e., agonists, having immunoregulatory effect against infections and cancer | ABBOTT LABORATORIES (US) | 1995-01-31 | — | — | US | claimed |
| EP-0564588-A4 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | — | 1993-12-29 | — | — | EP | claimed |
| EP-0564588-A1 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS. | ABBOTT LAB (US) | 1993-10-13 | — | — | EP | claimed |
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |
| WO-1992011858-A1 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-07-23 | — | — | WO | claimed |
| WO-1992012168-A1 | MODIFIED HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-07-23 | — | — | WO | claimed |
| EP-3472130-A1 | ALIPHATIC PROLINAMIDE DERIVATIVES | ORION OPTHALMOLOGY LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017222917-A1 | ALIPHATIC PROLINAMIDE DERIVATIVES | INCEPTION 4, INC. (US) | 2017-12-28 | — | — | WO | disclosed |
| EP-0564588-B1 | HEXAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | ABBOTT LAB (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5387671-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-02-07 | — | — | US | disclosed |
| US-5386011-A | Antiinflammatory agents; also, peptidomimetic compounds, i,e., agonists, having immunoregulatory effect against infections and cancer | ABBOTT LABORATORIES (US) | 1995-01-31 | — | — | US | disclosed |
| US-5190922-A | Antiinflammatory | ABBOTT LABORATORIES (US) | 1993-03-02 | — | — | US | disclosed |
| WO-1992021361-A1 | TERMINALLY MODIFIED TRI-, TETRA- AND PENTAPEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1992011858-A1 | HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-07-23 | — | — | WO | disclosed |
| WO-1992012168-A1 | MODIFIED HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-07-23 | — | — | WO | disclosed |