Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385585 | 0.83 | MAOB (0.50) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL30768511 | 0.80 | MAOB (0.50) | MAOBALOX5CYP4F2CYP4A11LMNA | |
| SCHEMBL1805526 | 0.80 | ALOX5 (0.56) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL25316002 | 0.80 | MAOB (0.53) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL31069846 | 0.76 | LMNA (0.67) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL281986 | 0.76 | LMNA (0.67) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL30769482 | 0.76 | MAOB (0.46) | MAOBLMNALTA4HBACE1NR4A2 | |
| SCHEMBL3823883 | 0.75 | MAOB (0.62) | MAOBALOX5CYP4F2CYP4A11LMNA | |
| SCHEMBL31748829 | 0.75 | MAOB (0.54) | MAOBALOX5CYP4F2CYP4A11LMNA | |
| SCHEMBL4891252 | 0.73 | MAOB (0.43) | MAOBALOX5LMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087907-A | Heteroaryl naphthalene as white (cell) triolefin biosynthesis inhibitor | MERCK FROSST CANADA INC (CA) | 1994-06-15 | — | — | CN | disclosed |