Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 15/20 | 0.65 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.65 |
| ▸ | BRD4 | O60885 | 7/20 | 0.55 |
| ▸ | BPTF | Q12830 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160804 | 0.76 | KAT2B (0.74) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL3250048 | 0.72 | KAT2B (0.63) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL17916626 | 0.71 | KAT2B (0.67) | KAT2BBPTF | |
| SCHEMBL23682831 | 0.71 | BPTF (1.00) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL3247038 | 0.71 | KAT2B (0.65) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL23718089 | 0.71 | KAT2B (0.56) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL979278 | 0.70 | KAT2B (0.60) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL9982691 | 0.70 | KDM4E (0.64) | KAT2BBRD9BRD4BPTF | |
| SCHEMBL17916635 | 0.69 | KAT2B (0.67) | KAT2BBPTF | |
| SCHEMBL17916627 | 0.69 | BPTF (1.00) | KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247571-C | Novel 2H -pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2006-03-29 | — | — | CN | disclosed |
| CN-1545513-A | Novel 2H -pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient | ����˹ҩ�﹤�� | 2004-11-10 | — | — | CN | disclosed |