Sugi Predict

Sugi Predict / Compounds / SCHEMBL979278

SCHEMBL979278

SCHEMBL979278

Cn1ncc(Cl)c(Cl)c1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KAT2B Q92831 5/20 0.60
▸ BRD9 Q9H8M2 4/20 0.60
▸ BPTF Q12830 5/20 0.50
▸ BRD4 O60885 3/20 0.50
▸ ALDH1A1 P00352 7/20 0.48
▸ HTT P42858 5/20 0.48
▸ MAPT P10636 5/20 0.48
▸ RAB9A P51151 5/20 0.48
▸ SMN1; SMN2 Q16637 4/20 0.48
▸ NPC1 O15118 4/20 0.48
▸ PAX8 Q06710 3/20 0.48
▸ MITF O75030 2/20 0.48
▸ S1PR4 O95977 2/20 0.48
▸ S1PR1 P21453 2/20 0.48
▸ THRB P10828 1/20 0.48
▸ XBP1 P17861 1/20 0.48
▸ GAA P10253 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ NPSR1 Q6W5P4 2/20 0.46
▸ LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17912386 0.98 KAT2B (0.58) KAT2BBRD9BPTFBRD4ALDH1A1
Tetrahydrofuran SCHEMBL28498059 0.86 KAT2B (0.47) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL30634726 0.85 KAT2B (0.46) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL14074017 0.80 KAT2B (0.58) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL2642056 0.80 KAT2B (0.53) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL8544499 0.80 BRD9 (0.48) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL15569189 0.79 ALDH1A1 (0.45) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL23755064 0.78 KAT2B (0.56) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL4163687 0.78 KAT2B (0.47) KAT2BBRD9BPTFBRD4ALDH1A1
SCHEMBL7010722 0.78 KAT2B (0.56) KAT2BBRD9BPTFBRD4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245461-A1 METHODS OF ACTIVATING FOXN1 THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
EP-4581025-A1 PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Auron Therapeutics, Inc. (US) 2025-07-09 — — EP disclosed
US-20250177408-A1 INHIBITOR OF INTERACTION BETWEEN YAP/TAZ AND TEAD, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF Etern Therapeutics Hongkong Limited (CN) 2025-06-05 — — US disclosed
EP-4484420-A1 INHIBITOR OF INTERACTION BETWEEN YAP/TAZ AND TEAD, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF Etern Biopharma (Shanghai) Co., Ltd. (CN) 2025-01-01 — — EP disclosed
US-12180221-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2024-12-31 — — US disclosed
WO-2024220843-A1 TECHNOLOGIES TARGETING CELL STATES AURON THERAPEUTICS, INC. (US) 2024-10-24 — — WO disclosed
CN-113754589-B Compositions, methods, and systems for synthesizing and using contrast agents 蓝瑟斯医学影像公司 2024-09-27 — — CN disclosed
US-20240308968-A1 FUNGICIDAL SUBSTITUTED HETEROCYCLES FMC CORP (US) 2024-09-19 — — US disclosed
EP-4387957-A1 FUNGICIDAL SUBSTITUTED HETEROCYCLES FMC Corporation (US) 2024-06-26 — — EP disclosed
EP-0352638-A2 5-Amino-6-pyridazinon-derivatives, process for their preparation and herbicidal agent containing them BASF Aktiengesellschaft (DE) 1990-01-31 — — EP disclosed
EP-0169375-B1 PROCESS FOR PRODUCING 2-TERT.-BUTYL-4,5-DICHLORO-3(2H)-PYRIDAZINONE NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-12-20 — — EP disclosed
EP-0283271-A2 Pyridazinone derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient UBE INDUSTRIES, LTD. (JP) 1988-09-21 — — EP disclosed
EP-0135076-B1 PYRIDAZINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BASF Aktiengesellschaft (DE) 1987-07-29 — — EP disclosed
US-4663324-A PRETREATMENT BASF AKTIENGESELLSCHAFT (DE) 1987-05-05 — — US disclosed
EP-0169375-A2 Process for producing 2-tert.-butyl-4,5-dichloro-3(2H)-pyridazinone NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-01-29 — — EP disclosed
US-4532239-A N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers CASSELLA AKTIENGESELLSCHAFT (DE) 1985-07-30 — — US disclosed
EP-0135076-A2 Pyridazinone derivatives, process for their preparation and their use as fungicides BASF Aktiengesellschaft (DE) 1985-03-27 — — EP disclosed
EP-0054946-B1 BASIC SUBSTITUTED PYRIDAZINES, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1984-08-15 — — EP disclosed
EP-0054946-A1 Basic substituted pyridazines, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1982-06-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12180221-B2 Compounds and uses thereof NLN, ACHE, CLN6 KAT2B 3054/4885BRD9 4027/4885BPTF 4676/4885
US-20250177408-A1 INHIBITOR OF INTERACTION BETWEEN YAP/TAZ AND TEAD, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF YAP1, YES1, TEAD2 KAT2B 3323/4885BRD9 878/4885BPTF 661/4885
US-20240308968-A1 FUNGICIDAL SUBSTITUTED HETEROCYCLES CYP1B1, CYP1A1, NOX1 KAT2B 3466/4885BRD9 2416/4885BPTF 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.