Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 15/20 | 0.74 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.74 |
| ▸ | BPTF | Q12830 | 6/20 | 0.58 |
| ▸ | BRD4 | O60885 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536539 | 0.76 | KAT2B (0.65) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL3250048 | 0.75 | KAT2B (0.63) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL13219471 | 0.74 | HTT (0.78) | — | |
| SCHEMBL23682831 | 0.73 | BPTF (1.00) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL3247038 | 0.73 | KAT2B (0.65) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL13219472 | 0.73 | RAB9A (0.79) | — | |
| SCHEMBL17912364 | 0.73 | KAT2B (0.56) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL979278 | 0.72 | KAT2B (0.60) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL9982691 | 0.72 | KDM4E (0.64) | KAT2BBRD9BPTFBRD4 | |
| SCHEMBL10823233 | 0.72 | KDM4E (0.56) | KAT2BBRD9BPTFBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |