SCHEMBL27536631

SCHEMBL27536631

CNC(=O)COc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
CYP2C9 P11712 1/20 0.64
CYP2C19 P33261 1/20 0.64
SMN1; SMN2 Q16637 3/20 0.61
HTT P42858 3/20 0.61
RAB9A P51151 2/20 0.61
GAA P10253 2/20 0.61
GLA P06280 1/20 0.61
PKM P14618 1/20 0.61
RECQL P46063 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 1/20 0.56
ALPL P05186 1/20 0.56
ALPI P09923 1/20 0.56
ALPG P10696 1/20 0.56
HPGD P15428 1/20 0.54
NPC1 O15118 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858346 0.93 PKM (0.63) SMN1; SMN2HTTRAB9AGAAPKM
Hydrochloric Acid SCHEMBL10955756 0.91 PKM (0.61) SMN1; SMN2HTTRAB9AGAAPKM
SCHEMBL27719104 0.85 L3MBTL1 (0.57) CYP1A2RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL14116960 0.85 PKM (0.49) CYP1A2CYP2C9CYP2C19SMN1; SMN2HTT
SCHEMBL13916156 0.84 KMT2A (0.54) CYP1A2CYP2C9CYP2C19SMN1; SMN2RAB9A
SCHEMBL17775464 0.84 ALOX15 (0.59) SMN1; SMN2RAB9APKMRECQLKDM4E
SCHEMBL4422103 0.83 MEN1 (0.66) CYP1A2CYP2C19SMN1; SMN2RAB9AGAA
SCHEMBL15145781 0.81 SMN1; SMN2 (0.63) CYP1A2CYP2C9CYP2C19SMN1; SMN2HTT
SCHEMBL6539261 0.81 PLA2G4B (0.60) PKMRECQLALDH1A1KMT2AMEN1
SCHEMBL171840 0.80 MEN1 (0.61) CYP1A2CYP2C9CYP2C19SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101279928-B N-methyl-2-[4-(4'-chlorophenoxy) phenoxy]acetamide and preparation thereof SHANGHAI INST TECHNOLOGY 2010-09-08 CN disclosed
CN-101279928-A N-methyl-2-[4-(4'-chlorophenoxy) phenoxy]acetamide and preparation thereof SHANGHAI INST TECHNOLOGY (CN) 2008-10-08 CN disclosed
CN-1281579-C N-methyl (p-phenoxy, phenoxy) acetamide and its preparation method SHANGHAI INST TECHNOLOGY (CN) 2006-10-25 CN disclosed