Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515312 | 0.83 | ALDH1A1 (0.91) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL28797466 | 0.82 | ALDH1A1 (0.59) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL19445756 | 0.81 | ALDH1A1 (0.81) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL20944746 | 0.81 | ALDH1A1 (0.76) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL20944758 | 0.81 | ALDH1A1 (0.76) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL20944749 | 0.81 | ALDH1A1 (0.76) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL11236668 | 0.80 | RAB9A (0.71) | ALDH1A1RAB9AL3MBTL1HPGDMAPT | |
| SCHEMBL506741 | 0.79 | NPC1 (0.57) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL24163448 | 0.79 | ALDH1A1 (0.74) | ALDH1A1RAB9AL3MBTL1KDM1AHPGD | |
| SCHEMBL25492959 | 0.79 | NPC1 (0.60) | ALDH1A1RAB9AHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1264843-C | Pyrazolopyrimidinone derivatives having PDE7 inhibitory action | DAIICHI SUNTORY PHARMACEUTICAL (JP) | 2006-07-19 | — | — | CN | disclosed |
| CN-1533392-A | Pyrazolopgrimidinone derivatives having PED 7 inhibitory activity | ��һ��������ҩ��ʽ���� | 2004-09-29 | — | — | CN | disclosed |