Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542357 | 0.92 | TAS1R3 (0.68) | RAB9AL3MBTL1ALDH1A1NPC1ATM | |
| SCHEMBL5482447 | 0.87 | RAB9A (0.56) | RAB9AL3MBTL1ALDH1A1NPC1SGMS2 | |
| SCHEMBL1753596 | 0.86 | RAB9A (0.55) | RAB9AL3MBTL1ALDH1A1NPC1SGMS2 | |
| SCHEMBL28688896 | 0.86 | RAB9A (0.61) | RAB9AL3MBTL1ALDH1A1NPC1SGMS2 | |
| SCHEMBL593297 | 0.85 | HTR4 (0.58) | RAB9AL3MBTL1NPC1ATMMEN1 | |
| SCHEMBL13081557 | 0.85 | TAS1R3 (0.56) | RAB9AL3MBTL1NPC1ATMMEN1 | |
| Hydrochloric Acid SCHEMBL594135 | 0.84 | HTR4 (0.57) | RAB9AL3MBTL1NPC1ATMMEN1 | |
| SCHEMBL16294450 | 0.84 | KMT2A (0.64) | RAB9ANPC1MEN1KMT2ATAS1R3 | |
| SCHEMBL14597963 | 0.83 | L3MBTL1 (0.65) | RAB9AL3MBTL1ALDH1A1NPC1HPGD | |
| SCHEMBL3771747 | 0.83 | KCNK3 (0.63) | RAB9AL3MBTL1NPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1264843-C | Pyrazolopyrimidinone derivatives having PDE7 inhibitory action | DAIICHI SUNTORY PHARMACEUTICAL (JP) | 2006-07-19 | — | — | CN | disclosed |
| CN-1533392-A | Pyrazolopgrimidinone derivatives having PED 7 inhibitory activity | ��һ��������ҩ��ʽ���� | 2004-09-29 | — | — | CN | disclosed |
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |