Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 6/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 4/20 | 0.47 |
| ▸ | GABRD | O14764 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812375 | 0.80 | KIF11 (0.79) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL13697482 | 0.80 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL28112759 | 0.79 | KIF11 (0.49) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL19768708 | 0.78 | AHR (0.59) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL12997524 | 0.77 | KIF11 (0.59) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL7031829 | 0.77 | AHR (0.53) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL31522706 | 0.77 | KIF11 (0.59) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL1734811 | 0.77 | AHR (0.57) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL22089502 | 0.77 | AHR (0.57) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL30196772 | 0.77 | AHR (0.57) | KDM4EMAPTALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128138-C | Carbazole alkaloid derivative and its prepn and use | CUI CHENGBIN (CN) | 2003-11-19 | — | — | CN | disclosed |
| CN-1332157-A | Carbazole alkaloid derivative and its prepn and use | CUI CHENGBIN (CN) | 2002-01-23 | — | — | CN | disclosed |