Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 5/20 | 0.41 |
| ▸ | GABRD | O14764 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12541283 | 0.79 | ADRB2 (0.46) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL27540731 | 0.79 | KDM4E (0.57) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL19768708 | 0.78 | AHR (0.59) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL31522706 | 0.77 | KIF11 (0.59) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL12997524 | 0.77 | KIF11 (0.59) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL4062550 | 0.74 | GABRP (0.61) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL31522704 | 0.74 | GABRP (0.61) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL31522707 | 0.74 | GABRP (0.61) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL869229 | 0.73 | AHR (0.53) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7031829 | 0.73 | AHR (0.53) | KIF11KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102743769-B | Imaging of beta-amyloid peptide and inhibition of beta-amyloid peptide aggregation | 香港浸会大学 | 2016-11-02 | — | — | CN | disclosed |