SCHEMBL27540751

SCHEMBL27540751

O=C(O)c1cnn(Cc2ccccc2)c1Nc1ccccc1[N+](=O)[O-]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
ASPH Q12797 1/20 0.48
KDM8 Q8N371 1/20 0.48
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
ALDH1A1 P00352 3/20 0.44
RAB9A P51151 3/20 0.44
GAA P10253 3/20 0.44
MAPK1 P28482 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
CASP7 P55210 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 1/20 0.43
ACHE P22303 1/20 0.43
BACE1 P56817 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
MYC P01106 1/20 0.42
CTSV O60911 1/20 0.42
CTSL P07711 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4837515 0.87 SMN1; SMN2 (0.48) ALDH1A1RAB9AGAAMAPK1NPC1
SCHEMBL27768216 0.81 AKR1C3 (0.52) KDM4EASPHKDM8AKR1C3AKR1C2
SCHEMBL453183 0.72 AKR1C3 (0.68) KDM4EASPHKDM8AKR1C3AKR1C2
SCHEMBL14052809 0.71 GAA (0.46) ALDH1A1GAAMEN1KMT2AMAPT
SCHEMBL14052805 0.70 GAA (0.55) ALDH1A1GAATDP1SMN1; SMN2PKM
SCHEMBL17869405 0.69 ALDH1A1 (0.54) ALDH1A1MEN1KMT2ALMNA
SCHEMBL38653331 0.69 PIN1 (0.46) ALDH1A1GAAPKM
SCHEMBL4213908 0.69 AKR1C3 (0.55) KDM4EASPHKDM8AKR1C3AKR1C2
SCHEMBL1496043 0.69 ALDH1A1 (0.48) ALDH1A1RAB9AGAAMAPK1TDP1
SCHEMBL30933991 0.69 ALDH1A1 (0.48) ALDH1A1RAB9AGAAMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100349896-C Benzamide derivatives as oxytocin agonists and vasopressin antagonists FERRING BV (NL) 2007-11-21 CN disclosed
CN-1285594-C Diazacycloalkanes as oxytocin agonists FERRING BV (NL) 2006-11-22 CN disclosed
CN-1751050-A Benzamide derivatives as oxytocin agonists and vasopressin antagonists FERRING BV (NL) 2006-03-22 CN disclosed
CN-1543467-A Diazacycloalkanes as oxytocin agonists 2004-11-03 CN disclosed