Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220167 | 0.80 | TSHR (0.42) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL9327547 | 0.75 | LMNA (0.58) | KDM4ESMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5790040 | 0.71 | — | — | |
| SCHEMBL17438169 | 0.68 | TSHR (0.48) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL577626 | 0.67 | NOS3 (0.45) | HIF1ATSHRNFKB1KDM4ETDP1 | |
| SCHEMBL9403622 | 0.65 | LMNA (0.52) | TSHRKDM4ESMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL16070672 | 0.63 | TSHR (0.41) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL8076390 | 0.63 | ABCB11 (0.46) | TAAR1TSHRALDH1A1CYP2C9 | |
| SCHEMBL16569535 | 0.63 | TSHR (0.41) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL16569237 | 0.63 | TSHR (0.41) | TAAR1HIF1AHTR3ATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101066962-A | Synthetic methods for polyphenols | MARS INC (US) | 2007-11-07 | — | — | CN | disclosed |
| CN-100341867-C | Method for synthesizing polyphenol | MARS INC (US) | 2007-10-10 | — | — | CN | disclosed |
| CN-1302295-A | Method for synthesizing polyphenol | MARS INC (US) | 2001-07-04 | — | — | CN | disclosed |