Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 3/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683146 | 0.76 | HRH3 (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CESR1 | |
| SCHEMBL1929134 | 0.73 | LTA4H (0.52) | SMN1; SMN2TSHRKDM4EALDH1A1MEN1 | |
| SCHEMBL1927451 | 0.73 | ESR1 (0.56) | ESR1ESR2SMN1; SMN2TSHRKDM4E | |
| SCHEMBL2810234 | 0.73 | KDM4E (0.56) | TSHRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1929274 | 0.72 | LTA4H (0.48) | SMN1; SMN2TSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL1928729 | 0.72 | KCNH2 (0.51) | SMN1; SMN2TSHRKDM4EALDH1A1HTR2C | |
| SCHEMBL1927551 | 0.72 | KCNH2 (0.51) | SMN1; SMN2TSHRKDM4EALDH1A1HTR2C | |
| SCHEMBL1929030 | 0.68 | LTA4H (0.50) | SMN1; SMN2KDM4EHRH3 | |
| SCHEMBL7549907 | 0.68 | HRH3 (0.47) | ESR1ESR2KDM4EHRH3 | |
| SCHEMBL2321726 | 0.68 | KDM4E (0.69) | TSHRKDM4EALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1263751-C | Novel compounds | ASTRAZENECA AB (SE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1541214-A | Novel compounds | — | 2004-10-27 | — | — | CN | disclosed |