Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706157 | 0.88 | L3MBTL1 (0.57) | CYP4F2CYP4A11TDP1LMNAALDH1A1 | |
| SCHEMBL13291593 | 0.87 | CYP4F2 (0.62) | CYP4F2CYP4A11LOXL2SLC7A5LMNA | |
| SCHEMBL5709931 | 0.85 | LMNA (0.59) | CYP4F2CYP4A11TDP1LMNAALDH1A1 | |
| SCHEMBL3033016 | 0.84 | LMNA (0.66) | CYP4F2CYP4A11LOXL2SLC7A5TDP1 | |
| SCHEMBL10174530 | 0.83 | SLC7A5 (0.63) | CYP4F2CYP4A11LOXL2SLC7A5LMNA | |
| SCHEMBL10174728 | 0.81 | CYP4F2 (0.56) | CYP4F2CYP4A11LOXL2SLC7A5LMNA | |
| SCHEMBL28743208 | 0.81 | LMNA (0.58) | LOXL2TDP1LMNAALDH1A1CYP1A2 | |
| SCHEMBL28280189 | 0.81 | CYP4F2 (0.76) | CYP4F2CYP4A11LOXL2ALDH1A1CYP1A2 | |
| SCHEMBL129801 | 0.80 | CYP4F2 (0.71) | CYP4F2CYP4A11LOXL2ALDH1A1TSHR | |
| SCHEMBL20306713 | 0.80 | SMN1; SMN2 (0.63) | CYP4F2CYP4A11LOXL2SLC7A5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1277809-C | Benzal indone and benzyl indone derivative(s), and its preparing method and use | UNIV ZHEJIANG (CN) | 2006-10-04 | — | — | CN | disclosed |
| CN-1709860-A | Benzal indone and benzyl indone derivative(s), and its preparing method and use | UNIV ZHEJIANG (CN) | 2005-12-21 | — | — | CN | disclosed |