Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | PNMT | P11086 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445345 | 0.86 | TAAR1 (0.58) | TAAR1PNMTRECQLTDP1KDM4E | |
| SCHEMBL28472579 | 0.86 | TSHR (0.53) | TAAR1PNMTSMN1; SMN2TSHRCASP1 | |
| SCHEMBL1293285 | 0.85 | TSHR (0.57) | SMN1; SMN2TSHRCASP1NR1H4KDM4E | |
| SCHEMBL27605961 | 0.84 | TSHR (0.55) | SMN1; SMN2TSHRCASP1NR1H4RECQL | |
| SCHEMBL9952446 | 0.84 | TSHR (0.55) | SMN1; SMN2TSHRCASP1NR1H4RECQL | |
| SCHEMBL18586486 | 0.83 | LCK (0.50) | TAAR1PNMTRECQLTDP1KDM4E | |
| SCHEMBL20077276 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRCASP1NR1H4RECQL | |
| SCHEMBL27810308 | 0.82 | TSHR (0.53) | SMN1; SMN2TSHRCASP1NR1H4RECQL | |
| SCHEMBL6554461 | 0.82 | HTR6 (0.56) | TAAR1PNMTSMN1; SMN2TSHRCASP1 | |
| SCHEMBL18740080 | 0.81 | RARB (0.49) | TAAR1PNMTNR1H4RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117070-C | Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4-tetrahydroquinoline carboxylic acids having retinoid-like biological activity | ALLERGAN SALES INC (US) | 2003-08-06 | — | — | CN | disclosed |
| CN-1214675-A | Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4-tetrahydroquinoline carboxylic acids having retinoid-like biological activity | VISION PHARM LP (US) | 1999-04-21 | — | — | CN | disclosed |
| CN-1211180-A | Method of treatment with compounds having RAG 'alpha' receptor specific or selective activity | ALLERGAN CO (US) | 1999-03-17 | — | — | CN | disclosed |