Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | PTPRG | P23470 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499388 | 0.86 | XDH (0.51) | TSHRCASP1SMN1; SMN2 | |
| SCHEMBL27543732 | 0.85 | TAAR1 (0.58) | TSHRCASP1SMN1; SMN2NR1H4ALDH1A1 | |
| SCHEMBL1671897 | 0.85 | ALDH1A1 (0.57) | TSHRCASP1SMN1; SMN2CSNK2A1ALDH1A1 | |
| SCHEMBL27768664 | 0.85 | ADRA1D (0.52) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KLKB1 | |
| SCHEMBL9558139 | 0.84 | TSHR (0.61) | TSHRCASP1SMN1; SMN2NR1H4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1671401 | 0.83 | ALDH1A1 (0.55) | TSHRCASP1SMN1; SMN2CSNK2A1ALDH1A1 | |
| SCHEMBL27618251 | 0.83 | LOXL2 (0.43) | CSNK2A1CSNK2A2CSNK2BCSNK2A3KLKB1 | |
| SCHEMBL30463143 | 0.82 | SMN1; SMN2 (0.59) | TSHRCASP1SMN1; SMN2NR1H4ALDH1A1 | |
| SCHEMBL543139 | 0.82 | SMN1; SMN2 (0.59) | TSHRCASP1SMN1; SMN2NR1H4ALDH1A1 | |
| SCHEMBL2140516 | 0.82 | TSHR (0.59) | TSHRCASP1SMN1; SMN2NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9408848-B2 | Fluorescent CDK inhibitors for treatment of cancer | GEORGETOWN UNIVERSITY (US) | 2016-08-09 | — | — | US | claimed |
| US-20110269178-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | GEORGETOWN UNIVERSITY (US) | 2011-11-03 | — | — | US | claimed |
| EP-2330908-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | Georgetown University (US) | 2011-06-15 | — | — | EP | claimed |
| WO-2010019967-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | claimed |
| CN-111094455-B | Resin composition, molded article, prepreg, fiber-reinforced molded article, and methods for producing these | ＡＧＣ株式会社 | 2022-06-17 | — | — | CN | disclosed |
| US-10982063-B2 | Resin composition, molded product and method for its production, prepreg and method for its production, and fiber-reinforced molded product and method for its production | AGC Inc. (JP) | 2021-04-20 | — | — | US | disclosed |
| US-20200157301-A1 | RESIN COMPOSITION, MOLDED PRODUCT AND METHOD FOR ITS PRODUCTION, PREPREG AND METHOD FOR ITS PRODUCTION, AND FIBER-REINFORCED MOLDED PRODUCT AND METHOD FOR ITS PRODUCTION | AGC Inc. (JP) | 2020-05-21 | — | — | US | disclosed |
| CN-111094455-A | Resin composition, molded article and method for producing same, prepreg and method for producing same, and fiber-reinforced molded article and method for producing same | ＡＧＣ株式会社 | 2020-05-01 | — | — | CN | disclosed |
| CN-110603138-A | Laser welded body and method for manufacturing same | 东方化学工业株式会社 | 2019-12-20 | — | — | CN | disclosed |
| US-9408848-B2 | Fluorescent CDK inhibitors for treatment of cancer | GEORGETOWN UNIVERSITY (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2159265-B1 | FLAME RETARDANT POLYAMIDE RESIN COMPOSITION | MITSUBISHI ENG PLASTICS CORP (JP) | 2015-12-02 | — | — | EP | disclosed |
| US-20110269178-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | GEORGETOWN UNIVERSITY (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2330908-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | Georgetown University (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20100160501-A1 | FLAME-RETARDANT POLYAMIDE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2159265-A1 | FLAME RETARDANT POLYAMIDE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2010-03-03 | — | — | EP | disclosed |
| WO-2010019967-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20090247596-A1 | THIOPHENECARBOXAMIDE DERIVATIVES AS EP4 RECEPTOR LIGANDS | MERCK CANADA INC. (CA) | 2009-10-01 | — | — | US | disclosed |
| EP-0344922-B1 | N-(N-(tetrahydropyrido(2,3-d)pyrimidinylmethyl)-aminomethylbenzoyl)glutamic acid derivatives | UNIV PRINCETON (US) | 1995-10-18 | — | — | EP | disclosed |
| US-4871746-A | N-[N-(tetrahydropyrido[2,3-D]pyrimidinylmethyl)-aminomethylbenzoyl]glutamic acid derivatives as neoplastic growth inhibitors | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247596-A1 | THIOPHENECARBOXAMIDE DERIVATIVES AS EP4 RECEPTOR LIGANDS | PTGER4, PTGER1, PTGER2 | TSHR 171/4885CASP1 4336/4885SMN1; SMN2 4859/4885 |
| US-20110269178-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | CDK3, CDK6, CDK8 | TSHR 3979/4885CASP1 2400/4885SMN1; SMN2 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.