Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939459 | 0.85 | CYP3A4 (0.36) | NQO2CYP3A4 | |
| SCHEMBL2713537 | 0.84 | NQO2 (0.37) | NQO2CYP3A4MAPK9MAPK8MAPK10 | |
| SCHEMBL27520501 | 0.83 | NQO2 (0.35) | NQO2CYP3A4ALOX5MAPK9MAPK8 | |
| SCHEMBL27518896 | 0.81 | NQO2 (0.33) | NQO2CYP3A4ALOX5MAPK9MAPK8 | |
| SCHEMBL28747896 | 0.79 | MAPK8 (0.36) | MAPK9MAPK8 | |
| SCHEMBL27543538 | 0.76 | GPR35 (0.38) | CYP3A4MAPK1 | |
| SCHEMBL27905445 | 0.75 | ALOX5 (0.36) | ALOX5MAPK1 | |
| SCHEMBL27892960 | 0.74 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL27778823 | 0.72 | GSK3B (0.33) | ALOX5 | |
| SCHEMBL27543527 | 0.71 | KDM4E (0.39) | CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1281591-C | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1416419-A | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2003-05-07 | — | — | CN | disclosed |