Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.74 |
| ▸ | MMP9 | P14780 | 20/20 | 0.74 |
| ▸ | MMP13 | P45452 | 17/20 | 0.74 |
| ▸ | ADAM17 | P78536 | 13/20 | 0.74 |
| ▸ | MMP3 | P08254 | 6/20 | 0.68 |
| ▸ | MMP7 | P09237 | 4/20 | 0.68 |
| ▸ | MMP2 | P08253 | 3/20 | 0.64 |
| ▸ | MMP8 | P22894 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608728 | 0.91 | MMP1 (0.61) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL6608718 | 0.91 | MMP1 (0.60) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL5636276 | 0.88 | MMP1 (0.73) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL27547263 | 0.84 | MMP1 (1.00) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL27547254 | 0.83 | MMP1 (0.85) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL27573230 | 0.82 | MMP1 (0.82) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL27547261 | 0.81 | MMP1 (0.75) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL27537608 | 0.81 | MMP1 (0.84) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL18313867 | 0.81 | MMP1 (1.00) | MMP1MMP9MMP13ADAM17MMP3 | |
| SCHEMBL29697336 | 0.80 | MMP8 (0.80) | MMP1MMP13MMP3MMP7MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1293663-A | 2,3,4,5-tetrahydro-1H-[1,4] benzodiazepine-3-hydroxamix acids as matrix metal-protease | AMERICAN CYANAMID CO (US) | 2001-05-02 | — | — | CN | claimed |