SCHEMBL27547876

SCHEMBL27547876

COc1cccc(C(=O)Cl)c1.c1cc2ccc1CO2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
PARP1 P09874 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.45
CTNNB1 P35222 2/20 0.44
WNT3A P56704 2/20 0.44
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
FAAH O00519 1/20 0.42
CNR2 P34972 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 2/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CBX7 O95931 1/20 0.41
CDYL2 Q8N8U2 1/20 0.41
CDYL Q9Y232 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1119594 0.88 CES2 (0.51) CES2CES1PARP1L3MBTL1CTNNB1
Methyl 3-Methoxybenzoate SCHEMBL3237334 0.86 SMN1; SMN2 (0.54) CES2CES1PARP1L3MBTL1CTNNB1
SCHEMBL27741000 0.86 PARP1 (0.68) CES2CES1PARP1L3MBTL1CTNNB1
SCHEMBL29626810 0.82 CES2 (0.71) CES2CES1PARP1NPC1RAB9A
SCHEMBL24402 0.82 CES2 (0.71) CES2CES1PARP1NPC1RAB9A
SCHEMBL27866506 0.82 NPC1 (0.47) CES2CES1PARP1L3MBTL1CTNNB1
Ethane SCHEMBL27287143 0.81 CES2 (0.69) CES2CES1PARP1NPC1RAB9A
1-Hydroxy-3-Methoxybenzene SCHEMBL27550933 0.79 ESR1 (0.47) CES2CES1NPC1RAB9AMEN1
SCHEMBL27580739 0.77 ACHE (0.61) L3MBTL1NPC1RAB9AMEN1KMT2A
SCHEMBL11705211 0.76 CES2 (0.62) CES2CES1PARP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1147298-C Prevention and curing agent for c attenuation living vaccine 卫材株式会社 2004-04-28 CN disclosed
CN-1137895-A Prevention and curing agent for c attenuation living vaccine EISAI CO LTD (JP) 1996-12-18 CN disclosed