Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775846 | 0.78 | ALDH1A1 (0.41) | HTR1AEGFRMAOAMAOBTSHR | |
| SCHEMBL6493726 | 0.77 | MEN1 (0.40) | HTR1AEGFRCHRM2CHRM4CHRM1 | |
| SCHEMBL6493723 | 0.77 | MEN1 (0.40) | HTR1AEGFRCHRM2CHRM4CHRM1 | |
| SCHEMBL27360942 | 0.77 | ICMT (0.37) | HTR1AICMTTSHR | |
| SCHEMBL7804957 | 0.76 | EGFR (0.35) | HTR1AEGFRMAOB | |
| SCHEMBL27885042 | 0.73 | KDM1A (0.38) | HTR1AEGFRCHRM2CHRM4CHRM1 | |
| SCHEMBL10812665 | 0.73 | KDM1A (0.38) | HTR1AEGFRCHRM2CHRM4CHRM1 | |
| SCHEMBL8806111 | 0.73 | CHRM2 (0.38) | HTR1AEGFRCHRM2CHRM4CHRM1 | |
| SCHEMBL2764548 | 0.72 | HTR1A (0.39) | HTR1AEGFRADRA1DCHRM2CHRM4 | |
| SCHEMBL8951708 | 0.72 | GAA (0.39) | HTR1AEGFRCHRNB2SLC6A2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1289771-A | 1,2-epoxide-1-(methylthiomethyl) phenylethane derivatives | SS PHARMACEUTICAL CO (JP) | 2001-04-04 | — | — | CN | disclosed |