Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067699 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308082 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308083 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25329304 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2140974 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12997194 | 0.83 | MAPT (0.44) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL24378366 | 0.82 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25340359 | 0.81 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL31253447 | 0.81 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Water SCHEMBL8124987 | 0.81 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141350-A1 | DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES | Ashvattha Therapeutics, Inc. | 2015-05-21 | — | — | US | disclosed |
| US-8889101-B2 | Dendrimer based nanodevices for therapeutic and imaging purposes | WAYNE STATE UNIVERSITY (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120003155-A1 | DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES | NATIONAL INSTITUTES OF HEALTH (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141350-A1 | DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES | PAM, MUC1, AADAC | LMNA 2887/4885MAPT 904/4885KDM4E 4773/4885 |
| US-20120003155-A1 | DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES | PAM, MUC1, AADAC | LMNA 2887/4885MAPT 904/4885KDM4E 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.