SCHEMBL308083

SCHEMBL308083

CC(=O)NC(CSSC[C@H](NC(C)=O)C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.59
KDM4E B2RXH2 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
NFKB1 P19838 1/20 0.59
PTGS2 P35354 1/20 0.59
THPO P40225 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ALDH1A1 P00352 2/20 0.57
ITGB1 P05556 3/20 0.47
ITGA4 P13612 3/20 0.47
TGFBR1 P36897 1/20 0.44
PRNP P04156 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
GNPAT O15228 1/20 0.40
PAM P19021 1/20 0.40
PSMB11 A5LHX3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140974 1.00 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL25329304 1.00 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL308082 1.00 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL24067699 1.00 MAPT (0.59) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL25340359 0.98 MAPT (0.57) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL31253447 0.98 MAPT (0.57) MAPTKDM4ETHRBALOX15NFKB1
Water SCHEMBL8124987 0.98 MAPT (0.57) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL24378412 0.94 MAPT (0.53) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL26864072 0.94 MAPT (0.53) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL12442995 0.91 MAPT (0.55) MAPTKDM4ETHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016813-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION Accencio LLC 2024-01-18 US claimed
US-11859203-B2 Cell culture methods UCB Biopharma SRL (BE) 2024-01-02 US claimed
US-20230372272-A1 USE OF CYSTINE AND DERIVATIVES THEREOF AS ANTI-THROMBOTIC AND THROMBOLYTIC AGENTS GEORGIA TECH RESEARCH CORPORATION 2023-11-23 US claimed
EP-4143161-B1 PROCESS OF MAKING N,N-DIACETYL-L-CYSTINE DISODIUM SALT FROM CYSTINE AND ACETYL CHLORIDE IN METHANOL IN THE PRESENCE OF SODIUM HYDROXIDE UNILEVER IP HOLDINGS B V (NL) 2023-11-01 EP claimed
EP-4143160-B1 PROCESS OF MAKING N,N'-DIACETYL-L-CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-11-01 EP claimed
EP-4142680-B1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-10-18 EP claimed
EP-3717631-B1 CELL CULTURE METHODS UCB Biopharma SRL (BE) 2023-08-30 EP claimed
EP-4216939-A1 USE OF CYSTINE AND DERIVATIVES THEREOF AS ANTI-THROMBOTIC AND THROMBOLYTIC AGENTS Georgia Tech Research Corporation (US) 2023-08-02 EP claimed
US-20230183176-A1 PROCESS OF MAKING N,N'-DIACETYL-L-CYSTINE CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-15 US claimed
US-20230157939-A1 PERSONAL CARE COMPOSITIONS WITH ENHANCED SOLUBILITY ACTIVES CONOPCO, INC., D/B/A UNILEVER (US) 2023-05-25 US claimed
EP-0727207-A1 The pharmacological use of certain cystine derivatives Astra Aktiebolag (SE) 1996-08-21 EP claimed
US-5441976-A Immunostimulants AKTIEBOLAGET ASTRA (SE) 1995-08-15 US claimed
US-5385904-A Organic salts of N,N'-diacetyl cystine AKTIEBOLAGET ASTRA (SE) 1995-01-31 US claimed
EP-0621862-A1 ORGANIC SALTS OF N, N'-DIACETYL CYSTINE. ASTRA AB (SE) 1994-11-02 EP claimed
WO-1993011104-A1 ORGANIC SALTS OF N, N'-DIACETYL CYSTINE AB ASTRA (SE) 1993-06-10 WO claimed
EP-0532595-A1 THE PHARMACOLOGICAL USE OF CERTAIN CYSTINE DERIVATIVES. ASTRA AB (SE) 1993-03-24 EP claimed
WO-1991018594-A1 THE PHARMACOLOGICAL USE OF CERTAIN CYSTINE DERIVATIVES AKTIEBOLAGET ASTRA (SE) 1991-12-12 WO claimed
US-4724239-A Method of treating chemical ulcers with N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine MORGAN LEE R (US) 1988-02-09 US claimed
US-4708965-A Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives MORGAN LEE R (US) 1987-11-24 US claimed
US-4379177-A Stable dehydrated cocrystalline amino acid food additives THE PROCTER & GAMBLE COMPANY (US) 1983-04-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183176-A1 PROCESS OF MAKING N,N'-DIACETYL-L-CYSTINE NAA15, DDC, NMT2 MAPT 1720/4885KDM4E 4395/4885THRB 3168/4885
US-20230157939-A1 PERSONAL CARE COMPOSITIONS WITH ENHANCED SOLUBILITY ACTIVES CUTA, CBS, SLC7A11 MAPT 609/4885KDM4E 2928/4885THRB 4847/4885
US-20240016813-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION ACE2, ACE, TMPRSS2 MAPT 1593/4885KDM4E 4306/4885THRB 3865/4885
US-20230372272-A1 USE OF CYSTINE AND DERIVATIVES THEREOF AS ANTI-THROMBOTIC AND THROMBOLYTIC AGENTS SERPINC1, SERPINE1, CTH MAPT 3961/4885KDM4E 4589/4885THRB 2120/4885
US-11859203-B2 Cell culture methods CBS, CTH, SLC7A11 MAPT 3657/4885KDM4E 3920/4885THRB 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.