Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27563430 | 1.00 | TP53 (0.42) | TP53CA1CA2PPARAFAAH | |
| Sulfuric Acid SCHEMBL28193719 | 0.98 | TP53 (0.43) | TP53CA1CA2PPARAFAAH | |
| Sulfuric Acid SCHEMBL17102602 | 0.98 | TP53 (0.43) | TP53CA1CA2PPARAFAAH | |
| Ammonia Solution, Strong SCHEMBL28786295 | 0.93 | CA2 (0.44) | TP53CA1CA2PPARAFAAH | |
| Sulfuric Acid SCHEMBL28266774 | 0.88 | TP53 (0.41) | TP53CA1CA2PPARAFAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL28273248 | 0.86 | EPHX1 (0.46) | FAAHEPHX1CES2CES1 | |
| Ammonia Solution, Strong SCHEMBL27408628 | 0.85 | TSHR (0.50) | EPHX1TSHRTHRB | |
| Bromide SCHEMBL27910948 | 0.83 | DNM1 (0.48) | EPHX1TSHRTHRB | |
| Bromide SCHEMBL28143418 | 0.83 | DNM1 (0.48) | EPHX1TSHRTHRB | |
| Ammonia Solution, Strong SCHEMBL27622204 | 0.83 | TSHR (0.47) | EPHX1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556214-B | A kind of preparation method of paracyanobenzoic acid | 大连奇凯医药科技有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-108948305-A | A kind of preparation method and applications of slow controlled release coated fertilizer | 五洲丰农业科技有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-104143494-B | There is the plasma processing chamber component that protective layer is formed in situ in plasma exposure face | 朗姆研究公司 | 2018-08-14 | — | — | CN | claimed |
| CN-108115309-A | A kind of metal product colophony type scaling powder | 天长市飞龙金属制品有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-108048774-A | A kind of metal surface hot dip coating method | 天长市飞龙金属制品有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-107556214-A | A kind of preparation method of paracyanobenzoic acid | 大连奇凯医药科技有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-105980391-A | Ex vivo methods for predicting and confirming in vivo metabolism of pharmaceutically active compounds | 昂皮瑞科公司 | 2016-09-28 | — | — | CN | claimed |
| CN-104774186-A | Herbicide isoxaflutole synthesis method | JIANGSU FLAG CHEMICAL INDUSTRY CO LTD | 2015-07-15 | — | — | CN | claimed |
| CN-104143494-A | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RES CORP | 2014-11-12 | — | — | CN | claimed |
| CN-103483470-A | Terminal group-functionalized polyethylene and preparation method thereof | CHINESE ACAD INST CHEMISTRY | 2014-01-01 | — | — | CN | claimed |
| CN-101885710-B | Method for preparing epoxy fatty acid methyl ester by using magnetic catalyst | INST CHEM IND FOREST PROD CAF | 2012-05-23 | — | — | CN | claimed |
| CN-101175739-B | Process for preparing difunctional epoxy monomers by selective oxidation of diolefin compounds | SHOWA DENKO KK | 2012-01-25 | — | — | CN | claimed |
| CN-102260312-A | Pollution-free reduction preparation method of estradiol and estradiol benzoate | — | 2011-11-30 | — | — | CN | claimed |
| CN-101974057-A | Preparation method of 16-dehydropregnenolone acetate and 16-dehydropregnenolone acetate congeners | UNIV TIANJIN | 2011-02-16 | — | — | CN | claimed |
| CN-101885710-A | Method for preparing epoxy fatty acid methyl ester by using magnetic catalyst | INST CHEM IND FOREST PROD CAF | 2010-11-17 | — | — | CN | claimed |
| CN-109824626-A | The method for being used to prepare 17 carbon -8- alkene of 17- oxabicyclo [14.1.0] | 西姆莱斯股份公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-109704944-A | It is a kind of the method for menthones to be prepared by citronellal and for the catalyst system of this method | 万华化学集团股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-1288122-C | Process for producing carbonyl compound | NAT INST OF ADVANCED IND SCIEN (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1639099-A | Process for producing carbonyl compound | NAT INST OF ADVANCED IND SCIEN (JP) | 2005-07-13 | — | — | CN | disclosed |
| CN-1399628-A | Methods for producing 2-(2-hydroxyphenyl)-2-(alkoxyimino)-n-methylacetamide derivatives | BAYER AG (DE) | 2003-02-26 | — | — | CN | disclosed |