Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HAAO | P46952 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317416 | 0.89 | TDP1 (0.58) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL2598195 | 0.87 | TDP1 (0.49) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL28300921 | 0.85 | TSHR (0.53) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL11669542 | 0.84 | TDP1 (0.47) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL28590951 | 0.84 | TDP1 (0.53) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL29561089 | 0.83 | TSHR (0.51) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL1355836 | 0.83 | TSHR (0.51) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL2263102 | 0.81 | TSHR (0.46) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL2381586 | 0.81 | TSHR (0.54) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL503509 | 0.81 | ALDH1A1 (0.48) | TDP1L3MBTL1TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162307-A | Heterocyclylamino and heterocyclyloxy-cycloalkenyl derivatives and their use as pest-control agents and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-15 | — | — | CN | disclosed |
| CN-1161034-A | Substituted cycloalkylamino and cycloalkoxy heterocycles, process for preparing the same and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-01 | — | — | CN | disclosed |
| CN-1161037-A | Substituted spiroalkylamino and spiroalkoxy heterocycles, process for their preparation and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-01 | — | — | CN | disclosed |