Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HAAO | P46952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561089 | 1.00 | TSHR (0.51) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL8671212 | 0.88 | TSHR (0.59) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL3478112 | 0.88 | TSHR (0.59) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL2381586 | 0.87 | TSHR (0.54) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL28300921 | 0.86 | TSHR (0.53) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL27505005 | 0.85 | TDP1 (0.44) | TSHRALDH1A1TDP1CYP3A4L3MBTL1 | |
| SCHEMBL27338694 | 0.85 | ALDH1A1 (0.42) | TSHRALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL27926224 | 0.83 | CES2 (0.47) | TSHRALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL8578465 | 0.83 | TSHR (0.50) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL503509 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1TDP1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230077362-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-03-16 | — | — | US | disclosed |
| EP-3998858-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | Corteva Agriscience LLC (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114072000-A | Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |
| WO-2021011722-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-01-21 | — | — | WO | disclosed |
| WO-2021011722-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-01-21 | — | — | WO | disclosed |
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION LLC (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION LLC (US) | 2013-09-19 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| EP-2379541-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010084067-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-29 | — | — | WO | disclosed |
| WO-2010084067-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-29 | — | — | WO | disclosed |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
| WO-2008048117-A2 | SYNTHESIS OF 5,6-DIMETHYL-9-OXO-9H-XANTHEN-4-YL- ACETIC ACID (DMXAA) | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-24 | — | — | WO | disclosed |
| CN-1044245-C | Tricyclic Dicarbonyl derivatives | HAFFMANN LA ROCHE AG F (DE) | 1999-07-21 | — | — | CN | disclosed |
| CN-1149295-A | Tricyclic Dicarbonyl derivatives | HOFFMANN LA ROCHE (CH) | 1997-05-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | TSHR 2352/4885ALDH1A1 106/4885TDP1 3463/4885 |
| US-20230077362-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | TSHR 2668/4885ALDH1A1 150/4885TDP1 490/4885 |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | HCAR2, HAO2, HK2 | TSHR 742/4885ALDH1A1 1863/4885TDP1 4185/4885 |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | TSHR 2352/4885ALDH1A1 106/4885TDP1 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.