SCHEMBL27550855

SCHEMBL27550855

O=C(Cl)C(Cl)Oc1cccc(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.51
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
WDR5 P61964 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.40
PARP1 P09874 1/20 0.40
BCHE P06276 1/20 0.40
SLC6A4 P31645 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11212800 0.80 MEN1 (0.42) KMT2AHPGDALOX15ALDH1A1LMNA
SCHEMBL11840833 0.80 OGG1 (0.50) OGG1KMT2AL3MBTL1KDM4EHPGD
SCHEMBL27604263 0.79 PPARG (0.47) HPGD
SCHEMBL10344330 0.78 OGG1 (0.50) OGG1KMT2AL3MBTL1RXRARXRB
SCHEMBL10637985 0.76 OGG1 (0.50) OGG1KMT2AL3MBTL1RXRARXRB
SCHEMBL10451483 0.75 OGG1 (0.56) OGG1KMT2AL3MBTL1KDM4EHPGD
SCHEMBL3884023 0.75 BCHE (0.50) OGG1KMT2ARXRARXRBRXRG
SCHEMBL28112032 0.74 PPARG (0.49) KMT2AL3MBTL1KDM4EALDH1A1MAPT
SCHEMBL10359842 0.73 OGG1 (0.58) OGG1KMT2AL3MBTL1KDM4EHPGD
SCHEMBL27665872 0.73 OGG1 (0.50) OGG1KMT2AL3MBTL1RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1319449-C Substituted phenoxy acetyl oxy alkyl phospho acid and phosphonate ester possessing bactericidal insecticidal activity UNIV HUAZHONG NORMAL (CN) 2007-06-06 CN disclosed
CN-1685825-A Substituted phenoxy acetyl oxy alkyl phospho acid and phosphonate ester possessing bactericidal insecticidal activity UNIV HUAZHONG (CN) 2005-10-26 CN disclosed