Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.47 |
| ▸ | PPARA | Q07869 | 16/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367795 | 0.83 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL27851337 | 0.82 | ALDH1A1 (0.46) | PPARGPPARA | |
| Hydrochloric Acid SCHEMBL11631504 | 0.82 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL11212800 | 0.81 | MEN1 (0.42) | PPARGPPARACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11279349 | 0.81 | PPARG (0.49) | PPARGPPARACYP1A2CYP2C9CYP2C19 | |
| Potassium Ion SCHEMBL11680365 | 0.80 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL11836379 | 0.80 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL27550855 | 0.79 | OGG1 (0.51) | HPGD | |
| SCHEMBL28264977 | 0.79 | HPGD (0.46) | PPARGPPARACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8761273 | 0.78 | CYP1A2 (0.57) | PPARGPPARACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641844-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109641853-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105722824-A | Heteroaryl linked quinolinyl modulators of ror[gamma]t | 詹森药业有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-100525763-C | Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors | TRANSTECH PHARMA INC (US) | 2009-08-12 | — | — | CN | disclosed |
| CN-100398523-C | 2,4-dichlor phenoxyacetic amide pyrimidine derivative and its preparation method and agricultural composition | UNIV SHANGHAI (CN) | 2008-07-02 | — | — | CN | disclosed |
| CN-101090723-A | Piperazine urea derivatives for the treatment of endometriosis | SCHERING AG (DE) | 2007-12-19 | — | — | CN | disclosed |
| CN-1869026-A | Substituted phenyloxy acetamide/propanmide midin derivatire with anticancer activity and its preparation method | UNIV SHANGHAI (CN) | 2006-11-29 | — | — | CN | disclosed |
| CN-1633290-A | Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors | TRANSTECH PHARMA INC (US) | 2005-06-29 | — | — | CN | disclosed |