Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491012 | 0.97 | PDK1 (0.37) | KDM4EALDH1A1LMNATSPOCTSV | |
| SCHEMBL27476015 | 0.88 | LTB4R (0.37) | ALDH1A1LMNACTSVCTSLL3MBTL1 | |
| SCHEMBL27472802 | 0.87 | PPARA (0.41) | ALDH1A1LTB4R2NPC1RAB9A | |
| SCHEMBL27474983 | 0.83 | PDK1 (0.39) | KDM4EALDH1A1TSPOL3MBTL1PDK1 | |
| SCHEMBL27489939 | 0.81 | KMT2A (0.33) | ALDH1A1TSHRLTB4R2 | |
| SCHEMBL27473239 | 0.79 | PPARA (0.37) | KDM4EALDH1A1 | |
| SCHEMBL27491346 | 0.78 | PPARA (0.40) | ALDH1A1LTB4R2 | |
| SCHEMBL27476016 | 0.75 | PPARA (0.43) | — | |
| SCHEMBL6579645 | 0.75 | AR (0.48) | ALDH1A1LMNAL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL6579278 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1LMNAL3MBTL1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |