Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758231 | 0.79 | MAOA (0.47) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL2718614 | 0.76 | MAOA (0.44) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL30583086 | 0.74 | MAOA (0.54) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL28220033 | 0.74 | MAOA (0.54) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL6345730 | 0.71 | USP5 (0.44) | MAOAMAOBERN1ALDH1A1MAPT | |
| SCHEMBL11295043 | 0.71 | ERN1 (0.55) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL201997 | 0.71 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL2125593 | 0.71 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL5745844 | 0.71 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL6822558 | 0.71 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1286815-C | 4-anilinoquinoline-3-carboxamides | ASTRAZENECA AB (SE) | 2006-11-29 | — | — | CN | disclosed |
| CN-1507434-A | Novel 4-anilinoquinoline-3-carboxamides | — | 2004-06-23 | — | — | CN | disclosed |