Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484258 | 0.97 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL27520001 | 0.96 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL27485275 | 0.96 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL7185196 | 0.95 | L3MBTL1 (0.41) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL27485661 | 0.93 | MMP8 (0.41) | NPC1RAB9AL3MBTL1MMP8ALDH1A1 | |
| SCHEMBL7188400 | 0.92 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL27499980 | 0.92 | TSHR (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL7186695 | 0.91 | LMNA (0.43) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7184689 | 0.91 | LMNA (0.43) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7182442 | 0.91 | LMNA (0.43) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |