Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118103 | 0.81 | ALOX15 (0.34) | TSHRALOX15 | |
| SCHEMBL5046445 | 0.79 | — | — | |
| SCHEMBL1764197 | 0.78 | ALOX15 (0.33) | ALOX15 | |
| SCHEMBL27869033 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27649068 | 0.76 | ALOX15 (0.36) | ALOX15 | |
| SCHEMBL28988214 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL16666609 | 0.74 | — | — | |
| SCHEMBL1763468 | 0.73 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL1020071 | 0.72 | ALDH1A1 (0.32) | TSHRALOX15 | |
| SCHEMBL19392125 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344245-A | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | WARNER LAMBER CO (US) | 2002-04-10 | — | — | CN | claimed |
| CN-1170811-C | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | ��ʲ | 2004-10-13 | — | — | CN | disclosed |
| CN-1344245-A | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | WARNER LAMBER CO (US) | 2002-04-10 | — | — | CN | disclosed |