Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794180 | 0.82 | MAOB (0.46) | MAOAMAOBTAAR1SLC6A2SLC6A4 | |
| SCHEMBL27574843 | 0.76 | LMNA (0.43) | SIGMAR1 | |
| SCHEMBL8580067 | 0.75 | MAOA (0.52) | MAOAMAOBTAAR1SLC6A2SLC6A4 | |
| SCHEMBL23820760 | 0.73 | CPN1 (0.43) | MAOAMAOBCPN1CPB2OPRK1 | |
| SCHEMBL27439241 | 0.72 | CYP3A4 (0.42) | MAOAMAOBCPN1CPB2SLC6A2 | |
| SCHEMBL27573550 | 0.72 | CYP3A4 (0.42) | MAOAMAOBCPN1CPB2SLC6A2 | |
| SCHEMBL10351218 | 0.71 | MAOA (0.53) | MAOAMAOBTAAR1SLC6A2SLC6A4 | |
| SCHEMBL15171130 | 0.71 | MAOA (0.46) | MAOAMAOBCPN1CPB2TAAR1 | |
| SCHEMBL16395906 | 0.70 | MAOA (0.52) | MAOAMAOBCPN1CPB2TAAR1 | |
| SCHEMBL9435383 | 0.70 | CYP3A4 (0.41) | MAOAMAOBCPN1CPB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1656107-A | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2005-08-17 | — | — | CN | claimed |
| CN-1332964-C | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2007-08-22 | — | — | CN | disclosed |
| CN-1656107-A | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2005-08-17 | — | — | CN | disclosed |