Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189265 | 0.96 | MMP8 (0.49) | MMP8TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL27554103 | 0.91 | KMT2A (0.46) | TDP1L3MBTL1KMT2AMEN1TP53 | |
| SCHEMBL27500957 | 0.90 | TDP1 (0.43) | MMP8TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL27499979 | 0.90 | MMP8 (0.52) | MMP8KMT2AMEN1MAPTCA12 | |
| SCHEMBL27499049 | 0.88 | TDP1 (0.44) | TDP1L3MBTL1 | |
| SCHEMBL27500594 | 0.88 | ALDH1A1 (0.41) | TDP1L3MBTL1KMT2AMEN1TP53 | |
| SCHEMBL27499976 | 0.88 | CA1 (0.45) | TDP1L3MBTL1KMT2ATP53CYP3A4 | |
| SCHEMBL27499966 | 0.87 | NPC1 (0.43) | TP53CYP3A4NPC1 | |
| SCHEMBL7183694 | 0.87 | KMT2A (0.45) | TDP1L3MBTL1KMT2AMEN1TP53 | |
| SCHEMBL7186621 | 0.86 | TDP1 (0.42) | MMP8TDP1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |