Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183694 | 0.96 | KMT2A (0.45) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL27554209 | 0.91 | MMP8 (0.50) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL27486290 | 0.89 | CA12 (0.49) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL27554201 | 0.88 | TDP1 (0.42) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL7189265 | 0.87 | MMP8 (0.49) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL27519981 | 0.87 | KMT2A (0.40) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL27499976 | 0.86 | CA1 (0.45) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL27500594 | 0.86 | ALDH1A1 (0.41) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL27500957 | 0.86 | TDP1 (0.43) | KMT2ACYP3A4TP53MAPTATM | |
| SCHEMBL7180203 | 0.84 | TDP1 (0.41) | KMT2ACYP3A4TP53MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |