Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144136 | 0.98 | TSHR (0.41) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL30100908 | 0.98 | TSHR (0.41) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL21201333 | 0.82 | ALDH1A1 (0.42) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL5642382 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL43548 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL2855511 | 0.76 | TSHR (0.48) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| Fluoride SCHEMBL28049696 | 0.76 | ALDH1A1 (0.48) | TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL10936424 | 0.74 | TSHR (0.46) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL249769 | 0.73 | — | — | |
| SCHEMBL156099 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165531-C | Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | — | 2004-09-08 | — | — | CN | disclosed |
| CN-1367785-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing substituted phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-09-04 | — | — | CN | disclosed |
| CN-1348446-A | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups | AMERICAN HOME PROD (US) | 2002-05-08 | — | — | CN | disclosed |
| CN-1335843-A | Thiourea inhibitors of herpes viruses | AMERICAN HOME PROD (US) | 2002-02-13 | — | — | CN | disclosed |
| CN-1333769-A | Thiourea inhibitors of herps viruses | AMERICAN HOME PROD (US) | 2002-01-30 | — | — | CN | disclosed |
| CN-1333750-A | Acetamide and substituted acetamide-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PROD (US) | 2002-01-30 | — | — | CN | disclosed |
| CN-1329608-A | Alpha-methylbenzyl-containing thioure a inhibitors of herpes viruses containing phenylenediamine group | AMERICAN HOME PROD (US) | 2002-01-02 | — | — | CN | disclosed |