SCHEMBL43548

SCHEMBL43548

Cc1cc(C)cc(N(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
TSHR P16473 6/20 0.50
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 3/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
TP53 P04637 1/20 0.41
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
NSD2 O96028 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
ACHE P22303 1/20 0.35
CHRM5 P08912 1/20 0.35
CHKA P35790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2855511 0.97 TSHR (0.48) ALDH1A1TSHRALOX15HSD17B10TDP1
Hydrochloric Acid SCHEMBL10936424 0.94 TSHR (0.46) ALDH1A1TSHRALOX15HSD17B10TDP1
SCHEMBL5642382 0.93 ALDH1A1 (0.50) ALDH1A1TSHRALOX15HSD17B10TDP1
Hydrochloric Acid SCHEMBL10936428 0.91 TSHR (0.44) ALDH1A1TSHRALOX15HSD17B10TDP1
SCHEMBL15928716 0.87 ALDH1A1 (0.60) ALDH1A1TSHRALOX15HSD17B10TDP1
SCHEMBL3234447 0.81 ALDH1A1 (0.57) ALDH1A1TSHRALOX15HSD17B10ACHE
SCHEMBL2144136 0.81 TSHR (0.41) ALDH1A1TSHRALOX15HSD17B10TDP1
SCHEMBL20033873 0.81 TSHR (0.41) ALDH1A1TSHRALOX15HSD17B10TDP1
SCHEMBL17204728 0.81 TSHR (0.41) ALDH1A1TSHRALOX15HSD17B10TDP1
SCHEMBL1724944 0.81 TSHR (0.41) ALDH1A1TSHRALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552956-B2 Photopolymerizable type dental surface coating composition SHOFU INC. (JP) 2026-02-17 US claimed
EP-3808787-A1 PHOTOCURABLE ADHESIVE COMPOSITION FOR MASCARA EXTENSION Zimmer, Margarita (DE) 2021-04-21 EP claimed
EP-3055364-B1 ROAD MARKING COMPOSITIONS AND USE THEREOF VELUVINE B V (NL) 2017-12-20 EP claimed
EP-3013787-B1 TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES COUNCIL SCIENT IND RES (IN) 2017-08-02 EP claimed
EP-3055364-A1 ROAD MARKING COMPOSITIONS AND USE THEREOF Veluvine B.V. (NL) 2016-08-17 EP claimed
WO-2015053632-A1 ROAD MARKING COMPOSITIONS AND USE THEREOF VELUVINE B.V. (NL) 2015-04-16 WO claimed
CN-102821737-B Dental adhesive material kit KURARAY NORITAKE DENTAL INC 2015-01-14 CN claimed
US-20110189253-A1 BIOMATERIAL COMPOSITION AND METHOD WARSAW ORTHOPEDIC, INC. (US) 2011-08-04 US claimed
US-6180739-B1 CYCLODEXTRINS WITH ACRYLATE AND ANHYDRIDES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 2001-01-30 US claimed
US-5910551-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1999-06-08 US claimed
EP-0043716-B1 PHOTOSENSITIVE COMPOSITION AND PATTERN FORMING PROCESS USING SAME Hitachi, Ltd. (JP) 1985-04-10 EP claimed
US-4409313-A Powder deposition to form pattern on light imaged photosensitive diazonium salt coating having salt of aromatic amine HITACHI, LTD. (JP) 1983-10-11 US claimed
US-4377630-A COMPRISING AN AROMATIC DIAZONIUM SALT AND N,N-DIALKYL ANILINE SALT HITACHI, LTD. (JP) 1983-03-22 US claimed
EP-0043716-A2 Photosensitive composition and pattern forming process using same Hitachi, Ltd. (JP) 1982-01-13 EP claimed
WO-1981002022-A1 PROVISIONAL CROWN-AND-BRIDGE RESIN IBSEN R (US) 1981-07-23 WO claimed
US-4235986-A ACRYLATE ESTER MONOMER NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-11-25 US claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-4128497-A TRISAZO DYE GENERAL ELECTRIC COMPANY (US) 1978-12-05 US disclosed
US-4116861-A DIAZO-STILBENE DYES GENERAL ELECTRIC COMPANY (US) 1978-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK ALDH1A1 675/4885TSHR 4509/4885ALOX15 1851/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885TSHR 4185/4885ALOX15 2690/4885
US-20110189253-A1 BIOMATERIAL COMPOSITION AND METHOD ILK, KIT, CAD ALDH1A1 1981/4885TSHR 4878/4885ALOX15 1075/4885
US-12552956-B2 Photopolymerizable type dental surface coating composition CDH1, DCLRE1A, ITGA1 ALDH1A1 50/4885TSHR 3987/4885ALOX15 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.