Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 15/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551588 | 0.74 | ADRA1D (1.00) | ADRA1DHRH3HRH4 | |
| SCHEMBL506596 | 0.66 | — | — | |
| SCHEMBL27551623 | 0.66 | ADRA1D (0.66) | ADRA1DHRH3HRH4 | |
| SCHEMBL7797453 | 0.66 | MGMT (0.35) | — | |
| Hydrochloric Acid SCHEMBL7809520 | 0.64 | MGMT (0.35) | — | |
| SCHEMBL2626817 | 0.64 | ADRA1D (0.63) | ADRA1DHRH3HRH4 | |
| SCHEMBL31284940 | 0.64 | HRH3 (0.47) | ADRA1DHRH3HRH4 | |
| SCHEMBL30476769 | 0.63 | ADRA1D (0.53) | ADRA1DHRH3HRH4 | |
| SCHEMBL8963903 | 0.63 | HRH3 (0.73) | HRH3HRH4 | |
| SCHEMBL349261 | 0.61 | ADRA1D (1.00) | ADRA1DHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1284066-A | Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors | ALLERGEN SALES INC (US) | 2001-02-14 | — | — | CN | disclosed |