Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787961 | 0.73 | FDPS (0.47) | — | |
| SCHEMBL349261 | 0.69 | ADRA1D (1.00) | ADRA1DHRH4HRH3 | |
| SCHEMBL27551588 | 0.68 | ADRA1D (1.00) | ADRA1DHRH4HRH3CYP3A4MAPT | |
| SCHEMBL5548998 | 0.67 | TAAR1 (0.47) | MAPT | |
| Immethridine SCHEMBL29462340 | 0.66 | HRH3 (1.00) | ADRA1DHRH4HRH3CYP3A4MAPT | |
| SCHEMBL6163997 | 0.66 | CYP17A1 (0.50) | HRH4HRH3CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL15223334 | 0.65 | — | — | |
| SCHEMBL5415171 | 0.65 | — | — | |
| SCHEMBL6167806 | 0.64 | NR1H3 (0.56) | HRH4HRH3CYP3A4SMN1; SMN2 | |
| SCHEMBL19368365 | 0.64 | ADRA2A (0.44) | CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4164690-A1 | SMALL MOLECULE VE-PTP INHIBITORS | Ripka, Amy (US) | 2023-04-19 | — | — | EP | disclosed |