Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320344 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL3641129 | 0.80 | L3MBTL1 (0.74) | KDM4EALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL3640898 | 0.79 | L3MBTL1 (0.72) | KDM4EALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL6234151 | 0.78 | MEN1 (0.62) | KDM4EALDH1A1MAPTLMNAACHE | |
| SCHEMBL1083795 | 0.77 | HTR3A (0.68) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL14585637 | 0.77 | LMNA (0.57) | KDM4EALDH1A1MAPTHPGDLMNA | |
| Hydrochloric Acid SCHEMBL6230920 | 0.77 | MEN1 (0.60) | KDM4EALDH1A1MAPTLMNAACHE | |
| SCHEMBL14262907 | 0.76 | LMNA (1.00) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL6231748 | 0.76 | HRH4 (0.58) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL30454930 | 0.76 | L3MBTL1 (0.97) | KDM4EALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283195-A | 1-(2-naphthyl) and 1(2-azanaphthyl)-4-(1-phenylmethyl)piperazines being dopamine D4 receptor subtype ligands | NEUROGEN CORP (US) | 2001-02-07 | — | — | CN | disclosed |