Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 18/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.49 |
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176566 | 0.72 | PGR (0.64) | PGRALDH1A1HSD17B10TDP1NR3C1 | |
| SCHEMBL11653695 | 0.72 | ALDH1A1 (0.56) | PGRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL8136368 | 0.71 | ALDH1A1 (0.46) | PGRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL4174714 | 0.70 | PGR (1.00) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL4174710 | 0.70 | PGR (1.00) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL12236649 | 0.69 | PGR (0.46) | PGRNR3C1ARNR3C2 | |
| SCHEMBL12236650 | 0.69 | PGR (0.56) | PGRNR3C1ARESR1NR3C2 | |
| SCHEMBL4170365 | 0.69 | PGR (0.67) | PGRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL29351296 | 0.68 | ALDH1A1 (1.00) | PGRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL940450 | 0.68 | ALDH1A1 (1.00) | PGRALDH1A1CYP3A4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172917-C | Steroid receptor modulator compounds and methods | ��λ��ҩ��ɷ�����˾ | 2004-10-27 | — | — | CN | claimed |
| CN-1626534-A | Steroid receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2005-06-15 | — | — | CN | disclosed |
| CN-1172917-C | Steroid receptor modulator compounds and methods | ��λ��ҩ��ɷ�����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1175247-A | Steroid receptor modulator compounds and methods | LIGAND PHARM INC (US) | 1998-03-04 | — | — | CN | disclosed |