Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 18/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.42 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011571 | 0.75 | PGR (0.63) | ALDH1A1HSD17B10PGRKDM4EHPGD | |
| SCHEMBL27556565 | 0.71 | PGR (0.57) | ALDH1A1CYP3A4HSD17B10TDP1PGR | |
| SCHEMBL11653695 | 0.68 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HSD17B10TDP1PGR | |
| SCHEMBL5498189 | 0.68 | PGR (0.47) | PGRNR3C1ARNR3C2 | |
| SCHEMBL4182318 | 0.65 | PGR (0.66) | ALDH1A1CYP3A4HSD17B10TDP1PGR | |
| SCHEMBL940450 | 0.65 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TDP1PGR | |
| SCHEMBL44875 | 0.65 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TDP1PGR | |
| SCHEMBL29351296 | 0.65 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TDP1PGR | |
| SCHEMBL4192784 | 0.63 | PGR (0.48) | ALDH1A1HSD17B10PGRKDM4EHPGD | |
| SCHEMBL9420120 | 0.63 | ALDH1A1 (0.96) | ALDH1A1CYP3A4HSD17B10TDP1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041066-A1 | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2000-10-04 | — | — | EP | disclosed |