Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.61 |
| ▸ | RARA | P10276 | 14/20 | 0.61 |
| ▸ | RARG | P13631 | 13/20 | 0.61 |
| ▸ | RXRA | P19793 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456673 | 0.84 | RARB (0.64) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL8101908 | 0.81 | RARB (0.72) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL10284325 | 0.80 | RARB (0.60) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL9186793 | 0.80 | RARB (0.63) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL7414449 | 0.79 | RARB (0.71) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL7567287 | 0.77 | RARB (0.69) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL8331112 | 0.77 | RARB (0.69) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL9187677 | 0.77 | RARA (0.64) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL10565430 | 0.77 | RARB (0.70) | RARBRARARARGRXRACYP3A4 | |
| SCHEMBL8907166 | 0.77 | RARB (0.56) | RARBRARARARGRXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285830-A | Pyridylpyrrole derivatives | SANKYO CO (JP) | 2001-02-28 | — | — | CN | disclosed |